![]() This score also identifies high-risk patients and determines whether an immediate invasive strategy would be beneficial in such patients ( 14 ). The TIMI risk score is valid and can be used for risk stratification of STEMI patients for better targeted treatment. Also, based on the ESSENCE trials and TIMI IIB study, the TIMI risk score incorporates the predictive factors of clinical characteristics, ECG changes, and cardiac biomarkers for risk assessment. Calibration was good for the overall study population and diabetics, with χ2 goodness of fit test p value of 0.936 and 0.983 respectively, but poor for those with renal impairment, χ2 goodness of fit test p value of 0.006. Background: Effective risk stratification is integral to management of acute coronary syndromes (ACS). Discrimination was good for the overall study population (c statistic 0.785) and in the high risk subgroups diabetics (c statistic 0.764) and renal impairment (c statistic 0.761). The TIMI risk score was strongly associated with 30-day mortality. Model discrimination and calibration was tested in the overall population and in subgroups of patients that were at higher risk of mortality i.e., diabetics and those with renal impairment.Ĭompared to the TIMI population, this study population was younger, had more chronic conditions, more severe index events and received treatment later. The TIMI risk score was evaluated in 4701 patients who presented with STEMI. This study sought to validate the Thrombolysis In Myocardial Infarction (TIMI) risk score for STEMI in a multi-ethnic developing country.ĭata from a national, prospective, observational registry of acute coronary syndromes was used. ![]() This is essential in developing countries with wide variation in health care facilities, scarce resources and increasing burden of cardiovascular diseases. ![]() Risk stratification in ST-elevation myocardial infarction (STEMI) is important, such that the most resource intensive strategy is used to achieve the greatest clinical benefit. ![]()
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